Science Corner

Science Corner

Current MVP projects

Thanks to the over 850,000 Veteran partners that have joined the Million Veteran Program (MVP), researchers are making important discoveries on a wide range of diseases and conditions that affect Veterans. Our current research includes: cancer, cardiovascular disease, diabetes, gene variation, Gulf War Illness, informatics, kidney disease, macular degeneration, mental health, osteoarthritis, Parkinson’s disease, post-traumatic stress disorder, substance use disorders, suicide prevention, TBI, tinnitus, and COVID-19.

Read more about some of our current MVP projects to learn how we’re helping to improve health.

Sign up for VA Research Updates.

Nurse and Patient

Predicting breast cancer risk

MVP is researching genetic and clinical markers to predict breast cancer risk in female Veterans.


Genetics and heart disease

MVP is looking at how obesity and lipid levels affect risk in African Americans and Hispanics.


Opioid sensitivity

MVP is identifying genetic predictors of sensitivity in order to better predict treatment option success.


Posttraumatic stress disorder (PTSD)

MVP is examining risk factors for developing PTSD in combat Veterans.

Leave a legacy of hope for future generations

The scientific spotlight shines on MVP

Male Having Ear Pain
Genetic Risk for Tinnitus Identified

A large genome-wide association study (GWAS) of self-reported tinnitus cases demonstrated that tinnitus can be inherited. Researchers found multiple genetic risk factors associated with tinnitus and also genetic correlations between tinnitus and hearing loss, insomnia, and neuropsychiatric disorders.

Breast Cancer Cells
Lipids Impact Breast Cancer Risk

In a study of up to 215,551 MVP partners, researchers found that genetically-inherited elevated cholesterol levels (both HDL and LDL) are associated with an increased risk of breast cancer.

3D Illustration Of Constricted And Narrowed Artery
Hemostatic Factors in Peripheral Artery Disease

Researchers found that Peripheral Artery Disease (PAD), a common circulatory problem in which narrowed arteries reduce blood flow to limbs, is impacted by genetically-inherited levels of some major blood clotting factors, but not others.

Schizophrenia and Bipolar Disorder One head Two faces
Schizophrenia and Bipolar Disorder in Veterans

In the largest and most diverse study of schizophrenia and bipolar disorder to date, researchers reported 52 new susceptibility indicators for the disorders in European and African American participants.

Pinpointing genetic locations linked to smoking and addiction

MVP researchers have identified new genetic information from smokers. What puts people at risk for becoming smokers or engaging in other addictive behavior? Researchers studied data on 209,000 Veterans to find out.

New strides in hypertension
New strides in hypertension

Large genome project leads to better understanding of high blood pressure. In an MVP project of over 300,000 participants, researchers have identified more than 200 new gene variants that could lead to high blood pressure.


Current MVP publications


MVP has published a wide variety of publications related to many areas of interest. 

Read more about some of our current publications using MVP data.

Archived articles
science meets technology

Unparalleled data meets world-class technology

The VA-DOE Big Data Science Initiative: the Department of Veterans Affairs and the Department of Energy are partnering to advance health care for Veterans through technology innovation.

Cholesterol genetics and new treatments

Cholesterol genetics and new treatments

MVP project on cholesterol genetics could lead to new treatments for heart disease and diabetes. Researchers have discovered gene mutations associated with better cholesterol and triglyceride levels.

Shedding light on resistant hypertension

Shedding light on resistant hypertension

MVP data leads to new finding on ‘resistant hypertension’. Researchers have identified the condition that gives those that have it a 23% higher risk of a heart attack.

DNA symbol with magnifying glass

Promoting the future of genetic testing

Million Veteran Program: A mega-biobank to study genetic influences on health and disease. MVP is designed to contribute to the development of precision medicine.